Integrating Corneal Collagen Crosslinking with Refractive Procedures (LASIK and PRK): A Comprehensive Review

Corneal collagen crosslinking is primarily carried out as a treatment modality for the management of corneal ectasias such as keratoconus, keratoglobus, pellucid marginal degeneration etc, as well as for the management of post refractive surgery corneal ectasias. However, it has evolved into a tool to strengthen the cornea in patients with borderline topography, who desire spectacle independence. This combined technique aims to enhance corneal strength and stability while maintaining visual acuity. However, careful patient selection, precise surgical planning, and understanding the biomechanical effects of crosslinking on the refractive outcome are essential to optimize the results. This article reviews the current evidence, risks, and considerations of simultaneous corneal collagen crosslinking and refractive surgery, highlighting its role in modern corneal and refractive surgery practices.